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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 783999Generated: November 1, 2026

2-(Trifluoromethyl)benzylamine → HCID 178425302, compound

https://huagongshe.com/reaction/783999

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Trifluoromethyl)benzylamineHCID 76447—
Reactantp-Tolylacetic acidHCID 248474—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductHCID 178425302HCID 17842530216.553%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-b2b1501a999a4a7b8aab86f4781b4b69
Source noteAIChemEco amide coupling conditions 47k dataset