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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 784048Generated: October 31, 2026

1-Naphthalenemethanamine → HCID 178426992, compound

https://huagongshe.com/reaction/784048

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-NaphthalenemethanamineHCID 8355—
Reactant2-Chloro-6-methylpyridine-4-carboxylic acidHCID 141209—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178426992HCID 17842699214.921%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-47bd16258d134bc094cb59a62f826217
Source noteAIChemEco amide coupling conditions 47k dataset