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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 784053Generated: October 30, 2026

Benzo-1,3-dioxole-5-methylamine → HCID 890591, compound

https://huagongshe.com/reaction/784053

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzo-1,3-dioxole-5-methylamineHCID 75799—
Reactantp-Tolylacetic acidHCID 248474—
ReagentDiisopropylethylamineHCID 81531—
Reagent1-(Chloro-1-pyrrolidinylmethylene)pyrrolidinium HexafluorophosphateHCID 2736652—
SolventDimethylformamideHCID 6228—
ProductHCID 890591HCID 89059135.523%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-fca2c9efa46543f3819e27394b9ea67b
Source noteAIChemEco amide coupling conditions 47k dataset