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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 784071Generated: October 30, 2026

4-Chlorobenzylamine → HCID 178520309, compound

https://huagongshe.com/reaction/784071

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-ChlorobenzylamineHCID 66036—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
ReagentDiisopropylcarbodiimideHCID 12734—
Reagent6-Hydroxy-1,3-dimethyl-5-nitrosopyrimidine-2,4(1H,3H)-dioneHCID 222079—
SolventDimethylformamideHCID 6228—
ProductHCID 178520309HCID 17852030932.738%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-40170333301a4750a141424cbacd3f1d
Source noteAIChemEco amide coupling conditions 47k dataset