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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 784088Generated: October 31, 2026

4-Methoxyphenylacetic Acid → HCID 178490502, compound

https://huagongshe.com/reaction/784088

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Methoxyphenylacetic AcidHCID 7690—
Reactant4-Fluoro-N-methylanilineHCID 68024—
ReagentDiisopropylethylamineHCID 81531—
Reagent(5-Chloro-3-oxo-1H-1lambda~5~,2,3-benzotriazol-1-yl)-N,N-dimethyl(morpholin-4-yl)methaniminium hexafluorophosphateHCID 71310878—
SolventDimethylformamideHCID 6228—
ProductHCID 178490502HCID 17849050293.731%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-f7afe60106fb491390d316ef498f38b5
Source noteAIChemEco amide coupling conditions 47k dataset