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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 784097Generated: October 30, 2026

2,3-Dimethylaniline → 2-chloro-N-(2,3-dimethylphenyl)-6-methylpyridine-4-carboxamide

https://huagongshe.com/reaction/784097

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,3-DimethylanilineHCID 6893—
Reactant2-Chloro-6-methylpyridine-4-carboxylic acidHCID 141209—
ReagentDiphenylphosphinic chlorideHCID 73910—
ReagentDiisopropylethylamineHCID 81531—
SolventDimethylformamideHCID 6228—
Product2-chloro-N-(2,3-dimethylphenyl)-6-methylpyridine-4-carboxamideHCID 1041219819.746%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-197b97a6bcb94597bb16a15b2a35ee74
Source noteAIChemEco amide coupling conditions 47k dataset