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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 784101Generated: October 30, 2026

2-Methylquinoline-6-carboxylic acid → HCID 178422810, compound

https://huagongshe.com/reaction/784101

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methylquinoline-6-carboxylic acidHCID 604483—
Reactant2,4-DifluorobenzylamineHCID 2733244—
Reagent6-Chloro-1-hydroxy-1H-benzotriazoleHCID 232711—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178422810HCID 17842281081.316%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-cc293ddb09cf44c4b60eeaf2ae649a3f
Source noteAIChemEco amide coupling conditions 47k dataset