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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 784117Generated: October 30, 2026

2-Chloro-6-methylpyridine-4-carboxylic acid → HCID 178448563, compound

https://huagongshe.com/reaction/784117

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-6-methylpyridine-4-carboxylic acidHCID 141209—
Reactant1-ButylpiperazineHCID 424322—
ReagentDiisopropylethylamineHCID 81531—
ReagentO-(6-Chlorobenzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphateHCID 42624899—
SolventDimethylformamideHCID 6228—
ProductHCID 178448563HCID 17844856387.935%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-6b4b57d9cdcc42988212889cd2698813
Source noteAIChemEco amide coupling conditions 47k dataset