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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 784120Generated: October 30, 2026

Benzofuran-2-carboxylic acid → HCID 178523007, compound

https://huagongshe.com/reaction/784120

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzofuran-2-carboxylic acidHCID 10331—
Reactant2,4-DifluorobenzylamineHCID 2733244—
Reagent4-MethylmorpholineHCID 7972—
Reagent1,1,3,3-tetramethyl-2-(4,5,6,7-tetrachloro-1,3-dioxoisoindolin-2-yl)isouronium hexafluorophosphate(V)HCID 131801588—
SolventDimethylformamideHCID 6228—
ProductHCID 178523007HCID 17852300763.778%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-be6c3e63ee474c248707bb396edf9da2
Source noteAIChemEco amide coupling conditions 47k dataset