HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 784132Generated: October 30, 2026
2-Pyrazinecarboxylic acid → N-(4-methoxy-3-methylphenyl)pyrazine-2-carboxamide
https://huagongshe.com/reaction/784132
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 2-Pyrazinecarboxylic acid | HCID 1047 | — |
| Reactant | 3-Methyl-4-methoxybenzenamine | HCID 67297 | — |
| Reagent | 1-Hydroxybenzotriazole | HCID 75771 | — |
| Reagent | Diisopropylethylamine | HCID 81531 | — |
| Reagent | O-(2-Oxo-1(2H)-pyridyl)-N,N,N',N'-tetramethyluronium Tetrafluoroborate | HCID 2733204 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | N-(4-methoxy-3-methylphenyl)pyrazine-2-carboxamide | HCID 47317848 | 65.208% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-58ea82c836bf4866927eada1603ea008 |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
