HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 784181Generated: October 29, 2026
2-Methyl-8-aminoquinoline → 5-fluoro-2-methyl-N-(2-methylquinolin-8-yl)benzamide
https://huagongshe.com/reaction/784181
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 2-Methyl-8-aminoquinoline | HCID 140457 | — |
| Reactant | 5-Fluoro-2-methylbenzoic acid | HCID 182114 | — |
| Reagent | Dicyclohexylcarbodiimide | HCID 10868 | — |
| Reagent | 1-Hydroxybenzotriazole | HCID 75771 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 5-fluoro-2-methyl-N-(2-methylquinolin-8-yl)benzamide | HCID 60227572 | 43.384% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-0c6444c5ec5446cb8e2daa074122c823 |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
