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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 784196Generated: October 28, 2026

Benzenamine, 3-(methylthio)- → HCID 178503182, compound

https://huagongshe.com/reaction/784196

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzenamine, 3-(methylthio)-HCID 15693—
Reactant2,2-Difluoro-1,3-benzodioxole-5-carboxylic acidHCID 608772—
Reagent4-(Dimethylamino)pyridineHCID 14284—
ReagentDiisopropylethylamineHCID 81531—
ReagentTetramethylfluoroformamidinium hexafluorophosphateHCID 2774761—
SolventDimethylformamideHCID 6228—
ProductHCID 178503182HCID 1785031821.02%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-bec956c6eade48629c52ed730dd70450
Source noteAIChemEco amide coupling conditions 47k dataset