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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 78422Generated: October 28, 2026

2-Bromoethyl methyl ether → 4-(4-chlorophenyl)-3-(2-methoxyethyl)-5-methyl-3H-thiazol-2-ylideneamine hydrobromide

https://huagongshe.com/reaction/78422

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Bromoethyl methyl etherHCID 80972—
Reactant4-(4-chlorophenyl)-5-methyl-1,3-thiazol-2-amineHCID 667574—
Product4-(4-chlorophenyl)-3-(2-methoxyethyl)-5-methyl-3H-thiazol-2-ylideneamine hydrobromideHCID 68623611—

Reaction Steps

A mixture of 4-(4-chlorophenyl)-5-methyl-thiazol-2-ylamine (420 mg, 1.87 mmol) and 2-bromoethyl methyl ether (600 μL, 6.40 mmol) was processed according to the method of Example 12A to provide the title compound: MS (DCI/NH3) m/z 283 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08841334B2
Source datasetuspto-grants-2014_09
ORD IDord-0162c755384c4a998ead25c9f472a8dd
Source noteuspto-grants-2014_09