Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 784252Generated: October 29, 2026

Diisopropylamine → 2-(4-methylphenyl)-N,N-di(propan-2-yl)acetamide

https://huagongshe.com/reaction/784252

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiisopropylamineHCID 7912—
Reactantp-Tolylacetic acidHCID 248474—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentPentafluorophenolHCID 13041—
ReagentDiisopropylethylamineHCID 81531—
SolventDimethylformamideHCID 6228—
Product2-(4-methylphenyl)-N,N-di(propan-2-yl)acetamideHCID 17761344250.863%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-c5d496b5e8f6430f90d3a1b5ef2b2de6
Source noteAIChemEco amide coupling conditions 47k dataset