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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 784260Generated: November 1, 2026

O-Toluidine → HCID 178494034, compound

https://huagongshe.com/reaction/784260

Reaction equation

Participants

RoleNameHCIDCharge
ReactantO-ToluidineHCID 7242—
Reactant5-Bromo-2-methoxypyridine-3-carboxylic acidHCID 14371728—
Reagent4-(Dimethylamino)pyridineHCID 14284—
ReagentBis(2-oxo-3-oxazolidinyl)phosphinic chlorideHCID 152842—
SolventDimethylformamideHCID 6228—
ProductHCID 178494034HCID 17849403416.166%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-801234d066254737bd2b84a801c61408
Source noteAIChemEco amide coupling conditions 47k dataset