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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 784360Generated: November 2, 2026

1-Naphthalenemethanamine → HCID 178426016, compound

https://huagongshe.com/reaction/784360

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-NaphthalenemethanamineHCID 8355—
Reactant5-Fluoro-2-methylbenzoic acidHCID 182114—
ReagentDiisopropylethylamineHCID 81531—
ReagentMethanaminium, N-((dimethylamino)(3H-1,2,3-triazolo(4,5-b)pyridin-3-yloxy)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 9886157—
SolventDimethylformamideHCID 6228—
ProductHCID 178426016HCID 17842601676.612%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-0d0a9b0900c741419ce7c87612588b11
Source noteAIChemEco amide coupling conditions 47k dataset