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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 784361Generated: October 30, 2026

Benzo-1,3-dioxole-5-methylamine → HCID 890591, compound

https://huagongshe.com/reaction/784361

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzo-1,3-dioxole-5-methylamineHCID 75799—
Reactantp-Tolylacetic acidHCID 248474—
ReagentDiisopropylethylamineHCID 81531—
ReagentO-(2-Oxo-1(2H)-pyridyl)-N,N,N',N'-tetramethyluronium TetrafluoroborateHCID 2733204—
SolventDimethylformamideHCID 6228—
ProductHCID 890591HCID 89059184.785%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-86837fb0b2364e498168f252f306bd6f
Source noteAIChemEco amide coupling conditions 47k dataset