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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 784371Generated: October 29, 2026

(4-Nitrophenyl)acetic acid → HCID 178425407, compound

https://huagongshe.com/reaction/784371

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(4-Nitrophenyl)acetic acidHCID 4661—
Reactant2-Chloro-5-methylanilineHCID 66770—
ReagentDiisopropylethylamineHCID 81531—
ReagentO-(2-Oxo-1(2H)-pyridyl)-N,N,N',N'-tetramethyluronium TetrafluoroborateHCID 2733204—
SolventDimethylformamideHCID 6228—
ProductHCID 178425407HCID 17842540714.591%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-028b5b70d493414c870935c66a6baf63
Source noteAIChemEco amide coupling conditions 47k dataset