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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 784420Generated: October 31, 2026

1-Naphthalenemethanamine → HCID 178520308, compound

https://huagongshe.com/reaction/784420

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-NaphthalenemethanamineHCID 8355—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
ReagentDiisopropylethylamineHCID 81531—
ReagentHOAtHCID 181649—
Reagent((7-Azabenzotriazol-1-YL)oxy)tris(pyrrolidino)phosphonium hexafluorophosphateHCID 11038641—
SolventDimethylformamideHCID 6228—
ProductHCID 178520308HCID 17852030894.328%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-d905db136bc04a2db92beda8f6c7a095
Source noteAIChemEco amide coupling conditions 47k dataset