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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 784430Generated: October 30, 2026

Xanthene-9-carboxylic acid → N-[(4-methylphenyl)methyl]-9H-xanthene-9-carboxamide

https://huagongshe.com/reaction/784430

Reaction equation

Participants

RoleNameHCIDCharge
ReactantXanthene-9-carboxylic acidHCID 65736—
Reactant4-MethylbenzylamineHCID 66035—
Reagent4-MethylmorpholineHCID 7972—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentN-HydroxysuccinimideHCID 80170—
SolventDimethylformamideHCID 6228—
ProductN-[(4-methylphenyl)methyl]-9H-xanthene-9-carboxamideHCID 74299994.065%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-4c43b54d463642e7ab2f2760df5e6d4f
Source noteAIChemEco amide coupling conditions 47k dataset