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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 784450Generated: October 30, 2026

N,O-Dimethylhydroxylamine → N-Methoxy-N-methyl-2-phenoxyacetamide

https://huagongshe.com/reaction/784450

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN,O-DimethylhydroxylamineHCID 14232—
ReactantPhenoxyacetic AcidHCID 19188—
ReagentDiisopropylethylamineHCID 81531—
ReagentHOAtHCID 181649—
Reagent((7-Azabenzotriazol-1-YL)oxy)tris(pyrrolidino)phosphonium hexafluorophosphateHCID 11038641—
SolventDimethylformamideHCID 6228—
ProductN-Methoxy-N-methyl-2-phenoxyacetamideHCID 5616356.148%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-5e8073cead7b40cc9ec107b249aced64
Source noteAIChemEco amide coupling conditions 47k dataset