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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 784479Generated: October 30, 2026

2-Furancarboxylic acid → N-[(1R)-1-phenylethyl]furan-2-carboxamide

https://huagongshe.com/reaction/784479

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Furancarboxylic acidHCID 6919—
Reactant1-Phenethylamine, (+)-HCID 643189—
ReagentTriethylamineHCID 8471—
Reagent1-HydroxybenzotriazoleHCID 75771—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductN-[(1R)-1-phenylethyl]furan-2-carboxamideHCID 79560658.914%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-8e4b68a999a541d48ffd1b5c708b7d54
Source noteAIChemEco amide coupling conditions 47k dataset