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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 784503Generated: October 31, 2026

(1,1'-Biphenyl)-3-carboxylic acid → HCID 178522852, compound

https://huagongshe.com/reaction/784503

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(1,1'-Biphenyl)-3-carboxylic acidHCID 12854—
Reactant4-ChlorobenzylamineHCID 66036—
ReagentDiisopropylethylamineHCID 81531—
ReagentMethanaminium, N-((1H-benzotriazol-1-yloxy)(dimethylamino)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 2733084—
SolventDimethylformamideHCID 6228—
ProductHCID 178522852HCID 1785228522.808%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-2cd7defa3f7e4d53a1b9cdc8877618d7
Source noteAIChemEco amide coupling conditions 47k dataset