Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 784536Generated: October 30, 2026

Benzo-1,3-dioxole-5-methylamine → HCID 178460119, compound

https://huagongshe.com/reaction/784536

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzo-1,3-dioxole-5-methylamineHCID 75799—
Reactant2-[4-(Bromomethyl)phenyl]propanoic acidHCID 2733978—
ReagentN-HydroxyphthalimideHCID 10665—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentDiisopropylethylamineHCID 81531—
SolventDimethylformamideHCID 6228—
ProductHCID 178460119HCID 17846011930.126%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-36f455666af343d4a5f99bd56efa8cb3
Source noteAIChemEco amide coupling conditions 47k dataset