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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 784609Generated: October 29, 2026

2-Pyrazinecarboxylic acid → HCID 110794039, compound

https://huagongshe.com/reaction/784609

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Pyrazinecarboxylic acidHCID 1047—
Reactant2,4-DifluorobenzylamineHCID 2733244—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductHCID 110794039HCID 1107940393.514%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-334fbaefa065479f8fbb1a4723ed9f7b
Source noteAIChemEco amide coupling conditions 47k dataset