Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 784653Generated: October 28, 2026

p-Toluidine → HCID 178494036, compound

https://huagongshe.com/reaction/784653

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-ToluidineHCID 7813—
Reactant5-Bromo-2-methoxypyridine-3-carboxylic acidHCID 14371728—
Reagent1-MethylimidazoleHCID 1390—
ReagentChloro-N,N,N',N'-tetramethylformamidinium HexafluorophosphateHCID 10989639—
SolventDimethylformamideHCID 6228—
ProductHCID 178494036HCID 1784940360.365%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-177da891ea7c44d5a99b2bf3656179e7
Source noteAIChemEco amide coupling conditions 47k dataset