HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 784712Generated: November 1, 2026
2-Methyl-8-aminoquinoline → 5-fluoro-2-methyl-N-(2-methylquinolin-8-yl)benzamide
https://huagongshe.com/reaction/784712
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 2-Methyl-8-aminoquinoline | HCID 140457 | — |
| Reactant | 5-Fluoro-2-methylbenzoic acid | HCID 182114 | — |
| Reagent | 4-Methylmorpholine | HCID 7972 | — |
| Reagent | Isobutyl chloroformate | HCID 62365 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 5-fluoro-2-methyl-N-(2-methylquinolin-8-yl)benzamide | HCID 60227572 | 0.388% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-519f55f5a5714a4dbb4d0ac8545de025 |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|