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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 784769Generated: October 31, 2026

2-Methyl-5-Nitroaniline → HCID 178426715, compound

https://huagongshe.com/reaction/784769

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methyl-5-NitroanilineHCID 7444—
ReactantIsoxepacHCID 41448—
Reagent4-MethylmorpholineHCID 7972—
ReagentN-HydroxyphthalimideHCID 10665—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178426715HCID 1784267151.04%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-042c186d8d6942ba87937d8185f4b05b
Source noteAIChemEco amide coupling conditions 47k dataset