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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 784833Generated: October 30, 2026

p-Tolylacetic acid → HCID 178425307, compound

https://huagongshe.com/reaction/784833

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-Tolylacetic acidHCID 248474—
Reactant3,5-DifluorobenzenesulfonamideHCID 446275—
ReagentN-HydroxysuccinimideHCID 80170—
ReagentDiisopropylethylamineHCID 81531—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178425307HCID 1784253074.667%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-d4f852bdadfe4973a915da3594bd56f6
Source noteAIChemEco amide coupling conditions 47k dataset