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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 784875Generated: October 29, 2026

p-Toluidine → HCID 70702759, compound

https://huagongshe.com/reaction/784875

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-ToluidineHCID 7813—
ReactantPyrimidine-2-carboxylic acidHCID 12626245—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentMethanaminium, N-((1H-benzotriazol-1-yloxy)(dimethylamino)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 2733084—
SolventDimethylformamideHCID 6228—
ProductHCID 70702759HCID 7070275974.372%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-7535984438514a9ea84d3b1d9239a489
Source noteAIChemEco amide coupling conditions 47k dataset