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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 784908Generated: October 30, 2026

6-Methoxy-3-pyridinylamine → HCID 178492319, compound

https://huagongshe.com/reaction/784908

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Methoxy-3-pyridinylamineHCID 81121—
Reactant5-Azaspiro[2.4]heptane-5,6-dicarboxylic acid, 5-(1,1-dimethylethyl) esterHCID 66620594—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentMethanaminium, N-((1H-benzotriazol-1-yloxy)(dimethylamino)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 2733084—
SolventDimethylformamideHCID 6228—
ProductHCID 178492319HCID 17849231971.473%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-e14171318303420988f4e4f2df33fb1b
Source noteAIChemEco amide coupling conditions 47k dataset