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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 78500Generated: October 25, 2026

2-Amino-4,5,6,7-tetrahydrobenzothiazole → 5-chloro-2-methoxy-N-(4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl)benzamide

https://huagongshe.com/reaction/78500

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-4,5,6,7-tetrahydrobenzothiazoleHCID 18046—
Reactant5-Chloro-o-anisic acidHCID 76970—
Product5-chloro-2-methoxy-N-(4,5,6,7-tetrahydro-1,3-benzothiazol-2-yl)benzamideHCID 887954—

Reaction Steps

Commercially available 4,5,6,7-tetrahydrobenzo[d]thiazol-2-amine (Aldrich) and 5-chloro-2-methoxybenzoic acid (Aldrich) were processed using the method described in Example 58 to afford the title compound. MS (ESI+) m/z 323 (M+H)+

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08841334B2
Source datasetuspto-grants-2014_09
ORD IDord-7515b7f9c20c467e9af985e09b193443
Source noteuspto-grants-2014_09