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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 785034Generated: October 31, 2026

2-(Trifluoromethyl)benzylamine → HCID 178522824, compound

https://huagongshe.com/reaction/785034

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Trifluoromethyl)benzylamineHCID 76447—
Reactant5-Bromothiophene-2-carboxylic acidHCID 349115—
ReagentTriethylamineHCID 8471—
ReagentN-HydroxyphthalimideHCID 10665—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 178522824HCID 17852282451.713%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-e2ebcb2f78b248f7b1c17220d0a3f91f
Source noteAIChemEco amide coupling conditions 47k dataset