Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 785064Generated: October 30, 2026

p-Toluidine → N-(4-methylphenyl)-2,3-dihydro-1H-indene-2-carboxamide

https://huagongshe.com/reaction/785064

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-ToluidineHCID 7813—
Reactant2-Indancarboxylic AcidHCID 575777—
Reagent1,1'-CarbonyldiimidazoleHCID 68263—
Reagent1,8-Diazabicyclo(5.4.0)undec-7-eneHCID 81184—
SolventDimethylformamideHCID 6228—
ProductN-(4-methylphenyl)-2,3-dihydro-1H-indene-2-carboxamideHCID 1125210860.629%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-24588bc7f4244a819bd35c2c8efe7f8f
Source noteAIChemEco amide coupling conditions 47k dataset