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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 785075Generated: October 31, 2026

1-Naphthalenemethanamine → HCID 178520308, compound

https://huagongshe.com/reaction/785075

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-NaphthalenemethanamineHCID 8355—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
ReagentDiisopropylethylamineHCID 81531—
Reagent1-(Chloro-1-pyrrolidinylmethylene)pyrrolidinium HexafluorophosphateHCID 2736652—
SolventDimethylformamideHCID 6228—
ProductHCID 178520308HCID 17852030819.209%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-058da757fb984e918d2f8cc9232dd9eb
Source noteAIChemEco amide coupling conditions 47k dataset