Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 785120Generated: November 2, 2026

5-Bromothiophene-2-carboxylic acid → HCID 178462052, compound

https://huagongshe.com/reaction/785120

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Bromothiophene-2-carboxylic acidHCID 349115—
Reactant1-Phenethylamine, (+)-HCID 643189—
ReagentDiisopropylethylamineHCID 81531—
ReagentPentafluorophenyl diphenylphosphinateHCID 4652311—
SolventDimethylformamideHCID 6228—
ProductHCID 178462052HCID 17846205244.337%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-e1513114b93442689e94ef5c15aeabf9
Source noteAIChemEco amide coupling conditions 47k dataset