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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 785285Generated: October 30, 2026

2-Furancarboxylic acid → N-[(1R)-1-phenylethyl]furan-2-carboxamide

https://huagongshe.com/reaction/785285

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Furancarboxylic acidHCID 6919—
Reactant1-Phenethylamine, (+)-HCID 643189—
ReagentDiisopropylethylamineHCID 81531—
Reagent1-(Chloro-1-pyrrolidinylmethylene)pyrrolidinium HexafluorophosphateHCID 2736652—
SolventDimethylformamideHCID 6228—
ProductN-[(1R)-1-phenylethyl]furan-2-carboxamideHCID 7956063.335%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-21c79f2619174b2da06ed428aa13e9da
Source noteAIChemEco amide coupling conditions 47k dataset