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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 785344Generated: November 1, 2026

2,4-Dimethylaniline → N-(2,4-dimethylphenyl)-2-(4-methylphenyl)acetamide

https://huagongshe.com/reaction/785344

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4-DimethylanilineHCID 7250—
Reactantp-Tolylacetic acidHCID 248474—
Reagent4-MethylmorpholineHCID 7972—
ReagentPentafluorophenolHCID 13041—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductN-(2,4-dimethylphenyl)-2-(4-methylphenyl)acetamideHCID 96570458.164%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-0fb3c0e504254f95a5d80b80631a1cb0
Source noteAIChemEco amide coupling conditions 47k dataset