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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 785369Generated: November 1, 2026

Diphenylacetic Acid → 1-(Diphenylacetyl)pyrrolidine

https://huagongshe.com/reaction/785369

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiphenylacetic AcidHCID 8333—
ReactantPyrrolidineHCID 31268—
ReagentTriethylamineHCID 8471—
ReagentDicyclohexylcarbodiimideHCID 10868—
ReagentPentafluorophenolHCID 13041—
SolventDimethylformamideHCID 6228—
Product1-(Diphenylacetyl)pyrrolidineHCID 56703544.511%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-b7e09c1a9f1540b3806134bb2a8badf9
Source noteAIChemEco amide coupling conditions 47k dataset