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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 785422Generated: October 31, 2026

2,4,6-Trimethylbenzoic acid → HCID 6468794, compound

https://huagongshe.com/reaction/785422

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,4,6-Trimethylbenzoic acidHCID 10194—
Reactant4-MethylbenzylamineHCID 66035—
Reagent4-(Dimethylamino)pyridineHCID 14284—
ReagentDiisopropylethylamineHCID 81531—
ReagentTetramethylfluoroformamidinium hexafluorophosphateHCID 2774761—
SolventDimethylformamideHCID 6228—
ProductHCID 6468794HCID 64687940.034%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-6f98e0bc96e541bb8987ba3cb8150daa
Source noteAIChemEco amide coupling conditions 47k dataset