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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 78545Generated: October 30, 2026

2-Bromoethyl methyl ether → 5-(4,4-Difluorocyclohexyl)-3-(2-methoxyethyl)thiazol-2(3h)-imine hydrobromide

https://huagongshe.com/reaction/78545

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Bromoethyl methyl etherHCID 80972—
ReactantHCID 66859799HCID 66859799—
Product5-(4,4-Difluorocyclohexyl)-3-(2-methoxyethyl)thiazol-2(3h)-imine hydrobromideHCID 66859539—

Reaction Steps

A mixture of Example 370E and commercially available 2-bromoethyl methyl ether (Aldrich) was processed using the method described in Example 12A to afford the title compound. MS (ESI−) m/z 277 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08841334B2
Source datasetuspto-grants-2014_09
ORD IDord-47651e57d76a403daa75c299751455f0
Source noteuspto-grants-2014_09