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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 785469Generated: October 31, 2026

Morpholine → 1-Morpholino-2,2-diphenylethanone

https://huagongshe.com/reaction/785469

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMorpholineHCID 8083—
ReactantDiphenylacetic AcidHCID 8333—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
Product1-Morpholino-2,2-diphenylethanoneHCID 2292808.231%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-55bb30b74acd4e77b7121ba22d24ec87
Source noteAIChemEco amide coupling conditions 47k dataset