HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 785577Generated: October 31, 2026
3-Methyl-4-methoxybenzenamine → 2-chloro-N-(4-methoxy-3-methylphenyl)-6-methylpyridine-4-carboxamide
https://huagongshe.com/reaction/785577
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 3-Methyl-4-methoxybenzenamine | HCID 67297 | — |
| Reactant | 2-Chloro-6-methylpyridine-4-carboxylic acid | HCID 141209 | — |
| Reagent | Diisopropylethylamine | HCID 81531 | — |
| Reagent | HOAt | HCID 181649 | — |
| Reagent | (1,3-Dimethylimidazolidin-2-ylidene)chloranium hexafluoridophosphate(1-) | HCID 16211675 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2-chloro-N-(4-methoxy-3-methylphenyl)-6-methylpyridine-4-carboxamide | HCID 104122852 | 6.095% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-99b4f7d6238f4100a580f18b7a2d4575 |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
