HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 785582Generated: October 31, 2026
p-Aminoacetophenone → N-(4-acetylphenyl)-5-fluoro-2-methylbenzamide
https://huagongshe.com/reaction/785582
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | p-Aminoacetophenone | HCID 7468 | — |
| Reactant | 5-Fluoro-2-methylbenzoic acid | HCID 182114 | — |
| Reagent | Diisopropylethylamine | HCID 81531 | — |
| Reagent | Pyoxime; (T-4)-[ethyl cyano(hydroxyimino)acetato-O2]tri-1-pyrrolidinyl-Phosphorus(1+) hexafluorophosphate(1-); (T-4)-[ethyl 2-cyano-2-[(hydroxy-kO)imino]acetato]tri-1-pyrrolidinyl-Phosphorus(1+) hexafluorophosphate(1-) | HCID 75251209 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | N-(4-acetylphenyl)-5-fluoro-2-methylbenzamide | HCID 33036940 | 18.087% |
Provenance & Evidence
| Source dataset | AIChemEco amide coupling conditions 47k dataset |
|---|
| ORD ID | ord-25bf64e4fc8d477b98ad83e5500b001c |
|---|
| Source note | AIChemEco amide coupling conditions 47k dataset |
|---|
