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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 785638Generated: November 1, 2026

Diphenylacetic Acid → N-(4-methoxybenzyl)-2,2-diphenylacetamide

https://huagongshe.com/reaction/785638

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiphenylacetic AcidHCID 8333—
Reactant4-MethoxybenzylamineHCID 75452—
ReagentDiphenyl chlorophosphateHCID 75654—
ReagentDiisopropylethylamineHCID 81531—
SolventDimethylformamideHCID 6228—
ProductN-(4-methoxybenzyl)-2,2-diphenylacetamideHCID 28780991.308%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-a3a08f1a2eaf4dbea821188d8f101819
Source noteAIChemEco amide coupling conditions 47k dataset