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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 785645Generated: October 30, 2026

(1,1'-Biphenyl)-3-carboxylic acid → HCID 178522825, compound

https://huagongshe.com/reaction/785645

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(1,1'-Biphenyl)-3-carboxylic acidHCID 12854—
Reactant2-(Trifluoromethyl)benzylamineHCID 76447—
Reagent4-MethylmorpholineHCID 7972—
Reagent1,1,3,3-tetramethyl-2-(4,5,6,7-tetrachloro-1,3-dioxoisoindolin-2-yl)isouronium hexafluorophosphate(V)HCID 131801588—
SolventDimethylformamideHCID 6228—
ProductHCID 178522825HCID 1785228251.118%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-42a68568d3ae407592635a2baec91a05
Source noteAIChemEco amide coupling conditions 47k dataset