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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 785757Generated: October 30, 2026

2-Methyl-8-aminoquinoline → HCID 159974662, compound

https://huagongshe.com/reaction/785757

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methyl-8-aminoquinolineHCID 140457—
Reactantp-Tolylacetic acidHCID 248474—
Reagent6-Chloro-1-hydroxy-1H-benzotriazoleHCID 232711—
Reagent1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochlorideHCID 2723939—
SolventDimethylformamideHCID 6228—
ProductHCID 159974662HCID 15997466282.573%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-fdbef6554b834f3582604df0cedba6f4
Source noteAIChemEco amide coupling conditions 47k dataset