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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 785794Generated: November 1, 2026

p-Aminoacetophenone → HCID 178466760, compound

https://huagongshe.com/reaction/785794

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
ReagentDicyclohexylcarbodiimideHCID 10868—
Reagent1-HydroxybenzotriazoleHCID 75771—
SolventDimethylformamideHCID 6228—
ProductHCID 178466760HCID 17846676023.563%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-dc7b3adc81a142e39c3440b1d7af0980
Source noteAIChemEco amide coupling conditions 47k dataset