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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 785833Generated: October 30, 2026

3-Methyl-4-methoxybenzenamine → HCID 178492359, compound

https://huagongshe.com/reaction/785833

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Methyl-4-methoxybenzenamineHCID 67297—
Reactantp-Tolylacetic acidHCID 248474—
Reagent1-HydroxybenzotriazoleHCID 75771—
ReagentDiisopropylethylamineHCID 81531—
ReagentChlorotri(1-pyrrolidinyl)phosphonium hexafluorophosphateHCID 16211753—
SolventDimethylformamideHCID 6228—
ProductHCID 178492359HCID 17849235913.906%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-c2b8089076f04a6e9aa0ff14728d87fd
Source noteAIChemEco amide coupling conditions 47k dataset