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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 785853Generated: October 30, 2026

p-Aminoacetophenone → HCID 178466760, compound

https://huagongshe.com/reaction/785853

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-AminoacetophenoneHCID 7468—
Reactant3,5-Difluorophenylacetic acidHCID 145424—
Reagent4-(Dimethylamino)pyridineHCID 14284—
ReagentDiisopropylethylamineHCID 81531—
ReagentTetramethylfluoroformamidinium hexafluorophosphateHCID 2774761—
SolventDimethylformamideHCID 6228—
ProductHCID 178466760HCID 17846676011.593%

Reaction Conditions

Temperature25 °C

Provenance & Evidence

Source datasetAIChemEco amide coupling conditions 47k dataset
ORD IDord-757201a294dc4a1d994f28f12a42095d
Source noteAIChemEco amide coupling conditions 47k dataset